This drug has been heralded as a major breakthrough in the fight against breast cancer.

They had minor breakthroughs but real success eluded them.

Biological research has often been a precursor to medical breakthroughs which benefit patients.

The leaders emphasized that a substantial breakthrough had been achieved. but there was more work to be done.

Researchers reported another important breakthrough in cancer research.

The first breakthrough cure for tuberculosis was streptomycin in the 1940s.

The year ahead isn`t expected to produce any breakthrough technologies.

I finally realized that the common factor in all these failed relationships was me. It was a breakthrough moment.

Her depiction of the young Queen Elizabeth was her breakthrough role.